1.To withdraw; to withhold; hence, reflexively, to keep at a distance; to cease to be familiar and friendly with. "We must estrange our belief from everything which is not clearly and distinctly evidenced." "Had we... estranged ourselves from them in things indifferent."
2.To divert from its original use or purpose, or from its former possessor; to alienate. "They... have estranged this place, and have burned incense in it unto other gods."
3.To alienate the affections or confidence of; to turn from attachment to enmity or indifference. "I do not know, to this hour, what it is that has estranged him from me." "He... had pretended to be estranged from the Whigs, and had promised to act as a spy upon them."
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